Search Results for "overdiagnosis"
NBC vastly exaggerates the potential benefits of lung cancer screening
…urther evaluation with imaging or clinical follow-up, which were predominantly done for benign disease. … Overdiagnosis and consequent overtreatment is a concern in lung cancer screening. The 1% to 2.7% prevalence of unrecognized lung cancer suggests a preclinical pool of lung cancer in high-risk populations. The clinical significance of these tumors is uncertain, but patients with lung cancer typically receive treatment, resulting in harm…4 10/9/2013
Beware the polyp police
…e-based arguments about whether they were doing more harm than good. The main issue has been the possibility of overdiagnosis. In the case of colon cancer, because most of us will have polyps and very few of us will die from them, screening is also liable to result in overdiagnosis and overtreatment. If and when polyps are found, people may live under a dark cloud, with a pre-cancerous label for the rest of their lives. They will certainly be m…
Five-star Friday (& some that didn’t make the list)
…ng Herald‘s story about an article by Ray Moynihan In the journal PLOS One: “Public Opinions about Overdiagnosis” – an Australian survey that concluded, “A small minority of Australians surveyed, including those reporting being screened for prostate or breast cancer, reported being informed of overdiagnosis; most believed people should be informed; and a majority felt it inappropriate that doctors with ties to pharm…12/10/2013
The potential harms of screening – seen this time in lung cancer screening
…there be harms from screening for cancer? Maybe the study published this week in JAMA Internal Medicine, “Overdiagnosis in Low-Dose Computed Tomography Screening for Lung Cancer,” will make some of the potential harms a little more clear. The analysis shows that nearly 20% of all lung cancers found by CT screening seemed to be harmless (indolent is the term the researchers used). The researchers wrote: “These patients may underg…4 1/12/2011
"Simple blood test" – cancer breakthrough or nightmare?
…diagnosis is a double-edged sword. While it has the potential to help some, it always has a hidden side-effect: overdiagnosis, the detection of abnormalities that are not destined to ever bother people in their lifetime. Becoming a patient unnecessarily has real human costs. There’s the anxiety of being told you are somehow not healthy. There’s the problem that getting a diagnosis may affect your ability to get health insurance. There…4/30/2012
Analysis of two Annals papers on benefits of mammography in younger women
…iopsy results, radiation exposure, false-negative results and false reassurance, pain related to the procedure, overdiagnosis (that is, diagnosis of tumors that are of no threat), and overtreatment. False-positive results are the most common and easily quantifiable harm. On the basis of statistics specific to U.S. practice patterns, about half of women getting an annual mammogram for 10 years starting at age 40 years will have at least 1 false-po…2/10/2011
Pioneer Press publishes my call for balance in cancer screening messages
…Here’s Why”) wrote about mammography in a medical journal: “The question is no longer whether overdiagnosis occurs, but how often it occurs.” He included the following table to explain the tradeoffs of harms and benefits (debits and credits) – and this was for 50-year old women, for whom the evidence of benefit is stronger than it is for those in their 40s. Welch explains, “The benefit of breast cancer screenin…10/30/2012
Were AP and AFP reporting on the same Lancet mammography paper?
…sten Jorgensen, a researcher at the Nordic Cochrane Centre in Copenhagen who has previously published papers on overdiagnosis. “It’s important they have at least acknowledged screening causes substantial harms,” he said, adding that countries should now re-evaluate their own programs. In the United States, a government-appointed task force recommends women at average risk of cancer get mammograms every two years starting at age…1/6/2012
Stop inappropriate, expensive & perhaps even unethical radical therapies for a condition that by itself does not kill
…re are ASCUS cells – or “atypical squamous cells of unknown significance.” Gleason 6 cells in the prostate cancer field have been called “adenosis.” They’ve been called IDLE – indolent lesions of epithelial origin. Whatever these cells are called, one practical goal for now is to educate men about the harms of overdiagnosis and overtreatment and offer active surveillance as a treatment option….5/28/2013
Journal editors decry the paradox of mental health: overtreatment and under-recognition
…example, http://www.alltrials.net). Conferences hosted by PharmedOut (http://www.pharmedout.org/) and Avoiding Overdiagnosis (http://www.preventingoverdiagnosis.net/) It concludes: “The largest challenge may be to recognize and prioritize mental health globallywith the requisite political visibility, funding, research, and attentionwithout reducing it to an object for disease mongering, pathologizing, and harmful over-treatment.” &…11/21/2012
General health checkups find lots of new problems but don’t cut morbidity/mortality
…isk for being diagnosed with false positives or negatives. Indeed, [the study authors] suggested that there was overdiagnosis — that routine checks tend to pick up conditions that were treated with no obvious benefit in terms of [illness] or mortality.” In his published commentary, MacAuley concluded that “policy should be based on evidence of well-being, rather than on well-meant good intentions” and rejects the notion th…2/4/2014
My weekly fix from Richard Lehman’s journal review blog
…udy of a pricey monoclonal antibody to address the epidemic of osteoporosis, i.e. a pharma-driven epidemic of overdiagnosis in older women. With a nice surrogate end point: bone mineral density, which bears an oblique relationship to fracture risk. And, in a market crowded with competing cheap agents, a placebo comparator.” “The editor of the NEJM, Jeff Drazen, has sat on the fence for two years on the question of open data from int…1/5/2015
Alan Cassels guest blog post: PSA test – good myths die hard
…e kinds of opinion columns and stories will continue to be produced, and the test, called the Poster Child for Overdiagnosis will continue to be offered to men. There is one incontrovertible fact in this story: That prostate cancer kills about 30,000 men a year. Everyone wishes there was a better test, but instead of dumping on the USPSTF and disagreeing with their evidence-based assessment of the test perhaps the urologists could admit that…1 9/9/2013
When the word “cancer” corrupts thought and action. Labeling hurts. The words matter.
…concluded that the increase was not a jump in the true occurrence of thyroid cancer, but rather, finding earlier abnormalities that might turn out to be benign. Overdiagnosis. Overtreatment. Impact on treatment decisions. Yes, the wording matters. ——————– Tweet Follow us on Twitter: https://twitter.com/garyschwitzer https://twitter.com/healthnewsrevu and on Facebook. …6/11/2011
Heart screening tests that should be screened more closely by consumers
…med hypochondriacs. In 1673, Molière pictured Fleurant, a money-hungry apothecary, as the supplier of unicorn’s horn to the “Imaginary Invalid”. Now, who will write the “Healthy unwitting”? We must recognize the discrepancy between the expected and the actual impact of screening in real life settings. Disease mongering and overdiagnosis are a source of harm. http://en.wikipedia.org/wiki/The_Imaginary_Invalid“…