Search Results for "overdiagnosis"
My weekly fix from Richard Lehman’s journal review blog
…udy of a pricey monoclonal antibody to address the epidemic of osteoporosis, i.e. a pharma-driven epidemic of overdiagnosis in older women. With a nice surrogate end point: bone mineral density, which bears an oblique relationship to fracture risk. And, in a market crowded with competing cheap agents, a placebo comparator.” “The editor of the NEJM, Jeff Drazen, has sat on the fence for two years on the question of open data from int…1/5/2015
Alan Cassels guest blog post: PSA test – good myths die hard
…e kinds of opinion columns and stories will continue to be produced, and the test, called the Poster Child for Overdiagnosis will continue to be offered to men. There is one incontrovertible fact in this story: That prostate cancer kills about 30,000 men a year. Everyone wishes there was a better test, but instead of dumping on the USPSTF and disagreeing with their evidence-based assessment of the test perhaps the urologists could admit that…1 9/9/2013
When the word “cancer” corrupts thought and action. Labeling hurts. The words matter.
…concluded that the increase was not a jump in the true occurrence of thyroid cancer, but rather, finding earlier abnormalities that might turn out to be benign. Overdiagnosis. Overtreatment. Impact on treatment decisions. Yes, the wording matters. ——————– Tweet Follow us on Twitter: https://twitter.com/garyschwitzer https://twitter.com/healthnewsrevu and on Facebook. …2 10/17/2013
Omega-3 fatty acids & prostate cancer: study and stories off-base
…the study were diagnosed based on an abnormal PSA test result, which is known to markedly increase the risk of overdiagnosis of prostate cancer–that is, finding cancers that would never cause harm during a mans lifetime. Overall, only 156 (18.7%) of cancers were high-grade (potentially aggressive). Furthermore, there were just 17 more high-grade cancers among men in the highest quartile of O3FA levels compared to the lowest quartile. Ev…9/15/2014
USA Today story shows lack of awareness of debate over pre-diabetes classification
…ely to develop diabetes in the next 10 years.” And it has an entire section on “Harms and risks of overdiagnosis.” Excerpt of that section: “There is a hazard in creating a pre-disease associated with a disease such as type 2 diabetes, which is itself little more than a risk factor. The biochemical diagnosis of type 2 diabetes is based on a surrogate endpoint. The downsides of being diagnosed with diabetes include the ne…5
Is it time to digitally re-examine the PSA test?
…entive Services Task Force gave the PSA test a definitive thumbs down due largely to the growing recognition of overdiagnosis. The USPSTF said that while the “benefits of the test were small”, the harms of this simple blood test which often begins a cascade of interventions that can end in “erectile dysfunction, urinary incontinence, bowel dysfunction, and a small risk for premature death.” This recommendation probably contributed to the sign…6/21/2010
NY Daily News begins second decade of evading evidence on PSA screening
…cial like this plays to our fears and prejudices. … Prostate cancer screening has resulted in substantial overdiagnosis and in unnecessary treatment. It may have saved relatively few lives. … The benefits of prostate cancer screening are still open to question. This means that informed or shared decision making should be done using the data now available before screening is performed. Some of the confusion of prostate cancer screening…1
Roundup of Media Messages on the New Mammogram Guidelines
…eened and that unlucky statistic were me.” However, we wonder if the story too casually dismisses the harms of overdiagnosis, and accepts (with no documentation) that overtreatment of carcinoma in situ will soon become avoidable. “In the not-so-far future, molecular tools may help physicians give those women a more accurate prognosis, Wender says, so those at lower risk can opt for less aggressive treatments — or simply watchful waiting.” USA To…9/16/2014
Evidence/balance lacking in Philly story on “Don’t Fear The Finger” campaign
…esting that, on this same day, the Wall Street Journal published a story, “Some Cancer Experts See ‘Overdiagnosis,’ Question Emphasis on Early Detection: Debate Among Doctors Looks at Whether Zealous Screening Leads to Overtreatment .” And that story quotes a respected urologist with a far different perspective than the one of the urologists in the Philadelphia Inquirer piece: “We have thrown the net very, very widel…4 7/11/2014
One physician’s story: An Egregious Example of Ordering Unnecessary Tests
…g my language. At last check, well more than 100 comments were left on the website in response to the article. I frequently write about the poor public dialogue about screening, overdiagnosis and overtreatment. This example brings home the point about why that’s important. —————– Tweet Follow us on Twitter: https://twitter.com/garyschwitzer https://twitter.com/healthnewsrevu and on Facebook. …8 2/6/2013
Five year survival rates can mislead – message to medical educators, medical journals, journalists and the public
…lier; this alone leads to higher survival at five years evenwhen patients do not live any longer. The second is overdiagnosis. Screening detects abnormalities that meet the pathological definition of cancer but that will never progress to cause symptoms or death (non-progressive or slow growing cancers). The higher the number of overdiagnosed patients, the higher the survival rate. In the US a larger proportion of men are screened by prostate spe…6/25/2014
Which journalists reported an extra dimension on the 3-D mammography story?
…y finds more cancers destined to kill people.” … Theres a debate about the harms of screening and overdiagnosis of breast cancers from mammograms and to me, this doesnt resolve that, said Dr. Etta Pisano, a breast imaging radiologist at the Medical University of South Carolina who wrote an editorial that accompanied the study. Some women may benefit more from tomosynthesis than others, such as those with dense breasts that tend to…10/4/2010
This is the way the Swedish mammography study could/should have been analyzed
…of the magnitude of the harms (including the experience of women with false positive results and the effects of overdiagnosis). Now, to look at the Swedish study, it is also worthwhile to note that these investigators have an obvious point of view from the start. Their previous papers (especially Tabar and Duffy) have all come to the same conclusion – that screening is a good idea. The Swedish data, and the Norwegian data (in the Sept. 23,…10/26/2011
British breast cancer screening now under independent review
…ional opinion acknowledging that breast cancer screening was not as good as used to be thought. The distress of overdiagnosis and decision making when finding lesions that might (or might not) be cancer that might (or might not) require mutilating surgery is increasingly being exposed. The oft repeated statement that “1400 lives a year are saved” has not been subjected to proper scrutiny. Even cancer charities use lower estimates. I e…1/10/2012
Another sponsored health news issue: retired columnist gets column back now paid by health care industry
…21; and should be addressed in the column? And how they will be addressed? Will, for example, untold stories of overdiagnosis and overtreatment be told in this health care provider-sponsored column? While the health care provider boasts on its website, “We were the first in the state to bring you CyberKnife and the first in the Lowcountry to offer the da Vinci robot,” will the column explore some of the growing questions about some of…