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Stopping clinical trials may distort evidence about risks and benefits

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A study in this week’s Journal of the American Medical Association, “Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects,” gives another troubling look at how inflated may be some of the claims about research findings.

One of the authors, Victor Montori, MD, of the Mayo Clinic, is quoted on a Mayo blog:

“.. almost everyone involved benefits from a trial ending early — doctors, researchers, funding sources,pharmaceutical firms, scientific journals, even reporters — everyone except the patient, who may end up receiving a therapy on the basis of misleading information about its benefits.”

He explains more on a YouTube video:

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