Terrific idea for a new medical journal series. Excerpt:
“Less is More,” a new series in the Archives, will highlight situations in which the overuse of medical care may result in harm and in which less care is likely to result in better health. For example, a series of articles in this issue of the Archives documents serious adverse effects of proton pump inhibitors, including increased rates of fractures, Clostridium difficile infection, and recurrence of diarrhea caused by C difficile; previous reports have also documented an increased risk of pneumonia. Harm will result if these commonly used medications are prescribed for conditions for which there is no benefit, such as nonulcer dyspepsia.