Sunscreen in a pill sounds very appealing – no more messy sunscreen. But to say that this supplement is still only experimental would be an understatement. To date, the only research that has been conducted has been in very small numbers of people (and animals) in experimental conditions, not the real world. Furthermore, little is known about how the pill compares to sunscreen. This story does a fair job of reporting on this approach while providing the reader with some cautionary information.
The story does mention that the supplement is available over the counter and describes the cost of treatment – $60 for 60 pills. The story should have compared this cost to sunscreen.
Although the story does mention the obvious alternative – sunscreen – it does not mention protective clothing, umbrellas, hats, or just staying out of the sun. The U.S. Preventive Services Task Force endorses many interventions to reduce risk of sun-related cancers, all of which are less costly alternatives to the dietary supplement covered in this article.
The story mentions two small but ‘rigorously designed’ studies, but this is not sufficient. To say they were small would be an understatement. Each study had 10 patients or fewer and were exposed to light under experimental conditions, not the real world and the results were not blinded. So the claims on which this article was based may be significantly overstated, although published in a peer-reviewed journal. The article relies heavily on information provided by the lead author of the study, whose work, at least, was funded by the manufacturer. We do not know that the other expert turned to for evaluation of this product is devoid of financial interest in this product. It would have been preferable to quote a spokesperson for an academic society or non-profit organization to provide some additional perspectives. The story does not quantify the benefits of treatment. The story says that “so far no negative side effects have been reported”. This is insufficient information on the harms (or potential harms) of the supplement.
Because this is a “dietary supplement” the company avoids the scrutiny of the FDA. That was not mentioned in the story, but should have been.
The story does mention the cost of treatment – $60 for 60 pills. The story should have compared this cost to the alternative – sunscreen.
The story does not quantify the benefits of treatment.
The story says that “so far no negative side effects have been reported.” This is insufficient.
The story mentions two small but ‘rigorously designed’ studies, but this is not sufficient. To say they were small would be an understatement. Each study had 10 patients or fewer and were exposed to light under experimental conditions – not the real world – and the results were not blinded.
The story does not overstate the risk of skin cancer. By focusing on sunburn, rather than skin cancer, the story avoids disease mongering.
The story quotes two physicians, one of whom is the lead author on the articles and was funded by the manufacturer of the product. It would have been preferable to quote a spokesperson for an academic society or non-profit organization to provide some additional perspectives.
Although the story does mention the obvious alternative – sunscreen, it does not mention protective clothing, umbrellas, hats, or just staying out of the sun period.
The story clearly states that this supplement is available over the counter.
The story does not comment on the novelty of this idea. Is oral sun protectant novel? The story should not leave it up to the reader to research whether this is a new idea or not.
There is no way to know if the story relied on a press release as the sole or main source of information.
Systematic, Criteria-Driven
The tale of two “negative” studies. Or, how spin is applied to make research findings look more impressive. A must read. https://johnmandrola.substack.com/p/the-tale-of-two-negative-studies
The @nytimes chose to interview one of the editors of the @AnnalsofIM (publisher of this paper) who "gushed with extraordinary glee: It’s huge! There are very few things that reduce your mortality by 30%."
Turns out coffee is not one of those few things despite all that glee. https://twitter.com/garyschwitzer/status/1533202075928215558
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