Diabetes is a huge public health problem, but it is also a rapidly evolving field of research. This story reports on the release of clinical trial results of a new class of diabetes drugs at the American Diabetes Association meeting.
Although the story claims that the pills are “experimental” and that the drug companies “hope to win FDA approval to begin selling them by year’s end”, this is not sufficient information on availability. The story should provide more insight about what phase of research the drugs are in and provide some justification for the proposed timeline for approval. Although the story does mention other diabetes drugs, the story does not elaborate on the advantages or disadvantages of the new drugs compared to existing drugs. Ultimately, it is not clear how these new drugs will fit with existing approaches.
Furthermore, iIn several places, the article leaves the reader with the impression that everyone with diabetes needs to have strict blood sugar control (i.e. A1C less than 7%). In reality, there is little data to support this.
The story provides quantification of benefits in relative terms only. (See “absolute vs. relative risk” under “Things you should know about research stories” on the home page of this site.) The story provides quantification of benefits in relative terms only. And it does not give enough details about the impact on weight loss, the amount of weight loss, or if people were able to maintain it. Although the story mentions two trials, the story does not provide adequate information on the strength of the available evidence. The story quotes an American Diabetes Associaiton official saying “The positive effects of the drugs, coupled with fewer of the negatives seen in other diabetes treatments, is what sets them apart.” But it doesn’t adequately explain or quantify those “fewer negatives.” It also says “Side effects of the pills include cold and flulike symptoms and headaches,” but doesn’t give any detail about how often these are seen.
The story does mention that the drugs are expensive, $3 to $6 a day compared to pennies a day for other diabetes drugs. What isn’t clear is whether these new drugs need to be taken in combination with older ones, which obviously increases the cost. The story does quote a vice president of the American Diabetes Association and a Merck employee, but could have quoted other clinicians or researchers who do not have a stake in the claims being made and who could provide some additional perspectives.
The story does mention that the drugs are expensive, $3 to $6 a day compared to pennies a day for other diabetes drugs. What isn’t clear is whether these new drugs need to be taken in combination with older ones, which obviously increases the cost.
The story provides quantification of benefits in relative terms only. And it does not give enough details about the impact on weight loss, the amount of weight loss, or if people were able to maintain it.
The story quotes an American Diabetes Associaiton official saying “The positive effects of the drugs, coupled with fewer of the negatives seen in other diabetes treatments, is what sets them apart.” But it doesn’t adequately explain or quantify those “fewer negatives.” It also says “Side effects of the pills include cold and flulike symptoms and headaches,” but doesn’t give any detail about how often these are seen.
Although the story mentions two trials, the story does not provide adequate information on the strength of the available evidence.
In several places, the article leaves the reader with the impression that everyone with diabetes needs to have strict blood sugar control (i.e. A1C less than 7%). In reality, there is little data to support this. This is disease mongering by implying that everyone with diabetes needs to have an A1C less than 7%.
The story does quote a vice president of the American Diabetes Association and a Merck employee. The story could have quoted other clinicians or researchers who do not have a stake in the claims being made and who could provide some additional perspectives. Nonetheless, we’ll give the story the benefit of the doubt and rate it satisfactory here.
Although the story does mention other diabetes drugs, the story does not elaborate on the advantages or disadvantages of the new drugs compared to existing drugs. Ultimately, it is not clear how these new drugs will fit with existing approaches.
Although the story claims that the pills are “experimental” and that the drug companies “hope to win FDA approval to begin selling them by year’s end”, this is not sufficient information on availability. The story should provide more insight about what phase of research the drugs are in and provide some justification for the proposed timeline for approval.
The story clearly states that these medications are the first in a new class of drugs.
We can’t be sure if the story relied on a press release as the sole source of information.
Systematic, Criteria-Driven
A great read on this weekend’s NYT claims of a cure for Type 1.
Cure for Type 1 diabetes? We’ve been down this road before with NY Times https://www.healthnewsreview.org/2021/11/cure-for-type-1-diabetes-weve-been-down-this-road-before-with-ny-times/
"But it is the framing and the emphasis of the #journalism by a leading science journalist at a leading newspaper that demands scrutiny. It has an impact on readers and on sick people that may cause harm by promoting false hope about extremely preliminary research"
👍👏💪 truth https://twitter.com/garyschwitzer/status/1465399358137024518
Why we should still miss healthnewsreview. https://twitter.com/garyschwitzer/status/1465399358137024518
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