This is a brief story about two studies of a topical skin treatment for excessive sweating, directed at an investor/financial audience.
The story has several major deficiencies, the most egregious being the lack of any specific, useful details of the new treatment, and the research so far conducted on it. We actually found the drug company’s news release to be more informative.
The story borders on disease mongering as well, since few details are given what makes this condition more than just a variation of a normal state of health.
While it may not be a disease per se, excessive sweating can be an embarrassing condition to live with, and new topical treatments would likely be welcomed by people who want to avoid oral medications, injections or surgery.
The product is not yet on the market, and is defined as experimental, so we’ll rate this as N/A. But readers would still benefit from seeing the projected steps needed to get on the market, which isn’t made clear here.
Not enough detail is contained in the description of the drug’s benefits: “a significant improvement in the severity of sweating was seen in 52.8 percent of the patients treated with the drug, compared with 28.3 percent patients in the control group, on a scale designed by the company. (and 66.1 percent versus 26.9 percent in the control group in the second trial).
How are we to know what this means when we don’t know how “improvement” or “severity” is measured?
No harms are mentioned, and given the lack of details on what the topical medication is made of, it would be difficult find out via independent research.
The story didn’t include enough information on the quality of the evidence. For example, how valid and reliable is the proprietary scale the drug company created to measure sweating? What are the measurement tool’s limitations? And the studies’ limitations? Also, the story didn’t indicate that this data hasn’t been reviewed by independent experts, nor published in a peer-reviewed journal.
We’re told in the story that about 3.9 million Americans suffer from excessive underarm sweating. But based on what analysis? What’s the source for that figure, and is it trustworthy?
A spokesperson from the company is quoted. However, no independent sources are used.
Many alternatives are mentioned, and that’s enough to skirt by as Satisfactory.
However, the discussion of alternatives (such as antiperspirants and Botox injections) seems mostly to revolve around pointing out how problematic they are, without any discussion of actual comparative effectiveness, which is a disservice to readers.
We learn it is still in its experimental stages.
The story makes no unfounded claims about novelty, and the story makes it clear that an effective topical treatment via wipes would be new for this condition.
The story didn’t appear to rely primarily on the news release, as we don’t see signs of quotes or text being lifted directly without acknowledgment. We’ll rate this N/A.
However, the release does have additional valuable context that we wish had been included (with acknowledgement), such as study details and adverse effects of the medication.
Systematic, Criteria-Driven
Monday at #ADA2021, an infectious disease epidemiologist, a journalist, and a researcher shared perspectives on communication of risk in the era of COVID-19: http://ow.ly/ROfR30rMeE7 @AstleyCM @garyschwitzer @berthahidalgo @ADA_DiabetesPro
Shoutouts to @susan_bewley @drkevinknopf @MichaelBaum11 in this call for more than fawning coverage from press releases for these kinds of stories.
Also, linked history inside goes back 5 years just on Grail apparently trying to become Holy Grail. https://twitter.com/garyschwitzer/status/1408849696416841731
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