The story reports on a University of Pennsylvania research study that probed 66 other studies, in what is known as a meta-analysis. Researchers examined how sleep deprivation — anything from three to four hours of sleep followed by 20 to 21 hours awake to no sleep for 36 straight hours — could ease depression symptoms. In studies they probed, 45 percent to 50 percent of patients reported feeling less depressed.
But the benefit does not last long, and the story wisely gives readers this context. This is something we wished had been emphasized in the news release on this study, which we also reviewed.
Depression is a major cause of disability in the US and around the world, with estimates that 16.1 million adults in the US had an episode in 2015, according to the National Institute of Mental Health. The most common treatment for depression is drugs, antidepressants, which don’t work for everyone and have side effects. This study of other studies was partly trying to narrow the focus on when sleep deprivation works in order to help researchers launch new studies to try to understand the mechanisms of this benefit. The story helps readers understand this: “He’s [researcher] not hoping to use sleep deprivation as a treatment but thinks that pinpointing what it does to the brain will help doctors develop other, more sustained treatments.”
The release does not mention costs. One may assume there is no cost to sleep deprivation but the deprivation in the studies was mostly monitored in inpatient facilities, which can be expensive.
The story just squeaks by on this, but we want to especially compliment the story for pointing out that the benefits are short-lived. While the story does not use a lot of numeric quantification, it does provide important context for how to view the study results.
Here’s what it says about benefits: “Their work confirmed that sleep deprivation — anything from three to four hours of sleep followed by 20 to 21 hours awake to no sleep for 36 straight hours — is indeed a powerful antidote to depression. In the 66 studies they analyzed, 45 percent to 50 percent reported feeling less depressed.”
But this is the part that puts a context around that for readers:
“That sounds great, but there’s a huge problem: For more than 80 percent of patients, the antidepressant effects are lost as soon as they get a good night’s rest. Repeated exposure to sleep deprivation has had mixed results.”
The story does not include the potential harms of sleep deprivation, which are extensive.
The story explains that the study was a meta-analysis of other studies, and it points out important limitations to help readers understand that quality of the evidence.
There was no disease mongering, and we thought the story did a good job of explaining the mysteries that still surround sleep’s relationship to mood. While sleep deprivation seems to create a temporary lifting of depression, it is also true that insomnia is a frequent symptom of depression. The story includes contradictions that remain to be resolved for researchers.
The story did not include any independent sources.
The story briefly hints at the other common treatments: drugs (notably antidepressants) and talk therapies like cognitive behavioral therapy.
The story explains it is not widely available as a therapeutic in clinics.
“Experts theorize that sleep deprivation may reset the circadian clock. But it is rarely used for treatment because it wears off so fast.
“I know of about three clinics worldwide that routinely use it,” Gehrman said. There are some studies showing that it can be helpful when combined with light or antidepressant medication treatment.”
The story explains that the study was novel primarily because of the meta-analysis approach.
The story does not rely on the news release, and demonstrates independent reporting by adding details and quotes that were not part of the release.
Systematic, Criteria-Driven
We’ve written about the hype of liquid biopsies for years (see link in comment below). And now this…. https://www.statnews.com/2022/01/12/medicare-shouldnt-cover-liquid-biopsies-early-cancer-detection/
Case counts still matter. “(There) are stories that may not be told adequately if only hospitalizations and deaths are emphasized.” @garyschwitzer interviewed by @dbauder of @AP. https://apnews.com/article/omicron-changing-news-outlets-covid-data-da9272f7c4c8a109c3bfb56bed9e9c76
My friend Gary @garyschwitzer wrote to his city council representative in a Minnesota town about a Viva Las Vegas event scheduled for January.
The response he got seems to perfectly capture where we are now.
https://www.healthnewsreview.org/2021/12/2021-ends-with-covid-craziness-in-sports-and-politics/
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